DSlocalizator is a normal module. after installing it will be available for every portal.
There are a few options that only persist between all portals: The hack installation, all the host options
You just need to install the hack once per DNN instance and localization will be active for all portals. Then you can go to each portal and enable the localization settings you want
TIP: DSlocalizator has an option to make the module as an admin module and inside the admin menu. After activating that option, DSlocalizator will be available on every portal as an admin option
Hope it helps